Obesity and Energetics Offerings

Featured

• Joseph R. Vasselli in Memoriam.
• Review: Impact on Oxidative Stress of Oral, High-Dose, Iron Supplementation for Management of Iron Deficiency After Bariatric Surgery.
• Pop Music Balanced Blood Sugar Levels in Mice, Thanks to Implanted Human Cells Rigged to Release Insulin Using a Sound-Sensitive Bacterial Protein.
• Phenotyping Obesity: A Focus on Metabolically Healthy Obesity and Metabolically Unhealthy Normal Weight.

Headline vs Study

• Headline: These 15 Foods in an Anti-Inflammatory Diet Could Treat Long COVID.
• Press Release: Could a Specialized Diet Alleviate Long COVID?
• Clinical Trial Registration: Registration of a Clinical Trial That Just Started.

Contrary or Null Findings

• RCT: No Impact on HbA1c or Secondary Outcomes Could Be Demonstrated Through the Acceptance and Commitment Therapy Based Programme.
• Meta-Analysis of RCTs: "Probiotics may have little to no effect on anthropometry in undernourished children, though there is considerable heterogeneity among the trials reviewed thus far."
• "Obesity increases the rate of non-invasive (NIV) and invasive mechanical ventilation (IMV) [with COVID-19 infection] but is not associated with a higher mortality rate when compared to the non-obese subgroup, this is contrary to what has been reported in the literature before."
• "Contrary to the hypothesis of a trade-off between egg mass and clutch size, we found that egg mass variation was not influenced by clutch size when accounting for allometric effects."
• From Reproductive Behaviour to Responses to Predators: Ocean Acidification Does Not Impact the Behaviour of an Herbivorous Marine Gastropod.
• Aerobic Exercise 3 Times Per Week in Adult Rats Did Not Influence the Progression of Periodontal Disease.
• AAV-Mediated Skeletal Muscle Specific Irisin Expression Does Not Contribute to Weight Loss in Mice.
• Fasting Reduces Satiety and Increases Hunger but Does Not Affect the Performance in Resistance Training.

Basic

• Biosynthesis and Biotechnological Production of the Anti-Obesity Agent Celastrol.
• GADD45A Regulates Subcutaneous Fat Deposition and Lipid Metabolism by Interacting with Stat1.
• RCT: Effects of Glyphosate Exposure on Western, Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice.
• Replacement of Saturated Fatty Acids with Linoleic Acid in Western Diet Attenuates Atherosclerosis in a Mouse Model with Inducible Ablation of Hepatic LDL Receptor.
• DHA Alleviated Hepatic and Adipose Inflammation with Increased Adipocyte Browning in High-Fat Diet-Induced Obese Mice.

Scientific Rigor & Scholarly Dialogue

• Retraction: Resveratrol Derivative, Trans-3, 5, 4′-Trimethoxystilbene, Prevents the Developing of Atherosclerotic Lesions and Attenuates Cholesterol Accumulation in Macrophage Foam Cells.
• Article: The Effectiveness of School-Based Interventions on Obesity-Related Behaviours in Primary School Children: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
• Letter: Unreliable Findings Due to Miscalculations and Errors. Comment on Nally Et Al. The Effectiveness of School-Based Interventions on Obesity-Related Behaviours in Primary School Children: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Children 2021, 8, 489.
• “Important” Findings in Child Obesity with No Significance.

Clinical

• Meta-Analysis: Effect of Alpha-Linolenic Acid Supplementation on Cardiovascular Risk Profile in Individuals with Obesity or Overweight.
• Visceral and Ectopic Fat are More Predictively Associated with Primary Liver Cancer Than Overall Obesity from Genetic Sights: A Mendelian Randomization Study.
• RCT: Relationship between Peer Mentoring for Physical Activity and Cardiometabolic Health.
• Meta-Analysis: Effect of Caper Fruit (Capparis spinosa L.) Consumption on Liver Enzymes, Lipid Profile, Fasting Plasma Glucose, and Weight Loss.
• Review: Adult Obesity Management for Primary Care.

Children and Adolescents

• Successful Obesity Treatment Does Not Harm, but Rather Normalizes, the Growth Velocity Pattern Among Children.
• Systematic Review: The Impact of Ultra-Processed Foods on Obesity and Cardiometabolic Comorbidities in Children and Adolescents.
• Factors Associated with Antihypertensive Therapy Prescription in Youth Delaware Medicaid Recipients with Primary Hypertension Diagnosis.
• Systematic Review: Exercise and Insulin Resistance Markers in Children and Adolescents with Excess Weight.

Surgery

• Barrett`s Esophagus in Bariatric Surgery: Regression or Progression?
• Meta-Analysis: Effect of Bariatric Surgery on Serum Amyloid a Protein.
• Bariatric Surgery and Calcifediol Treatment, Gordian Knot of Severe-Obesity-Related Comorbidities Treatment.
• Systematic Review: Closure of Gastrocutaneous Fistula Following Bariatric Surgery.

Drugs

• Essential Oil Components with Antidiabetic and Anti-Obesity Properties: A Review of Mechanisms of Action and Toxicity.
• Synthesis, Characterization and Biological Evaluation of Some New Isoxazole and Pyrazole Compounds for Anti-Obesity Drug.
• Glucagon-Modified Liposomes Delivering Thyroid Hormone for Anti-Obesity Therapy.
• Approved Anti-Obesity Medications in 2022 KSSO Guidelines and the Promise of Phase 3 Clinical Trials: Anti-Obesity Drugs in the Sky and on the Horizonopen Access.
• Metformin Use Is Associated with Decreased Asthma Exacerbations in Adolescents and Young Adults.
• Video: What T2D Therapy Have You Considered for Your Patients After Metformin?

Food & Diet

• RCT: Almonds Vs. Carbohydrate Snacks in an Energy-Restricted Diet: Weight and Cardiometabolic Outcomes.
• Systematic Review: Time-Restricted Feeding and Intermittent Fasting as Preventive Therapeutics.
• RCT: High- and Normal-Protein Diets Improve Body Composition and Glucose Control in Adults with Type 2 Diabetes.
• An Oldie but Goodie: Hormonal Responses to a Fast-Food Meal Compared with Nutritionally Comparable Meals of Different Composition.
• Review: Metabolic Changes Following Intermittent Fasting.
• Intermittent Fasting and Bone Health: A Bone of Contention?

Caloric and Dietary Restriction

• RCT: Head-To-Head Comparison of BAM15, Semaglutide, Rosiglitazone, NEN, and Calorie Restriction on Metabolic Physiology in Female db/db Mice.
• Response to a Low-Energy Meal Replacement Plan on Glycometabolic Profile and Reverse Cardiac Remodelling in Type 2 Diabetes: A Comparison between South Asians and White Europeans.

Exercise & Physical Activity

• Article: A Perspective on High-Intensity Interval Training for Performance and Health.
• Editorial: Potential Impact of Wearables on Physical Activity Guidelines and Interventions: Opportunities and Challenges.

Economics & Sociology

• Causal Effect of Obesity on the Probability of Employment in Women in Turkey.
• Preprint: Associations between Dietary Behaviours and Mental and Physical Health Among Swedish Adolescents: The Role of Socioeconomic and Demographic Status.
• Association of Socioeconomic Factors and Dietary Intake with Sarcopenic Obesity in the Korean Older Population.

Epidemiology

• Exposure to Air Pollution and Gains in Body Weight and Waist Circumference Among Middle-Aged and Older Adults.
• Systematic Review: The Global Prevalence of Overweight and Obesity Among Nurses.
• Spatiotemporal Variations and Determinants of Overweight/Obesity Among Women of Reproductive Age in Urban India During 2005-2021.
• Long-Term Exposure to Walkable Residential Neighborhoods and Risk of Obesity-Related Cancer in the New York University Women’s Health Study.
• Understanding the Dynamics of the Obesity Transition Associated with Physical Activity, Sedentary Lifestyle, and Consumption of Ultra-Processed Foods in Colombia.
• Risk Factors for Overweight and Obesity After Childhood Acute Lymphoblastic Leukemia in North America and Switzerland: A Comparison of Two Cohort Studies.
• Anthropometric and DXA-Derived Measures of Body Composition in Relation to Pre-Diabetes Among Adults.

Psychology & Neuroscience

• Longitudinal Relationship between Adolescents' Mental Health, Energy Balance-Related Behavior, and Anthropometric Changes.
• The Impact of BMI on the Clinical Features of Bipolar Disorder: A STEP-BD Study.

Equity and Disparities

• Lifestyle Patterns in European Preschoolers: Associations with Socio-Demographic Factors and BMI.
• Metabolic Dysfunction-Associated Steatotic Liver Disease in Older Adults Is Associated with Frailty and Social Disadvantage.

Stigma

• The Weight Stigma Heat Map: A Tool to Identify Weight Stigma in Public Health and Health Promotion Materials.
• Parental Communication About Body Weight and Adolescent Health: The Role of Positive and Negative Weight-Related Comments.

Policy Related

• Prospective Associations of Neighborhood Healthy Food Access and Walkability with Weight Status in a Regional Pediatric Health System.
• Traffic Light Nutrition Labeling Preferences Among Children.
• In-Store Marketing and Supermarket Purchases: Associations Overall and by Transaction SNAP Status.
• The Development and Potential of a Digital Out of Home Food Environment Monitoring Platform.

Intergenerational Effects

• High Maternal Free Thyroxine (FT4) During Pregnancy May Be Associated with the Decreasing Risk of Obesity and Low Body Fat Ratio in 6-Year-Old Children.
• Mother's Warmth from Maternal Genes: Genomic Imprinting of Brown Adipose Tissue.

Ecology, Evolution, & Energetics

• From Newtonian Concepts to a Quantum Understanding: The Evolution of Endocrinology and Metabolism.
• Gut Microbiota in the Pathogenesis and Therapeutic Approaches of Diabetes.

Methods

• An Interpretable Machine Learning Model of Cross-Sectional U.S. County-Level Obesity Prevalence Using Explainable Artificial Intelligence.
• Optimal Study Designs for Cluster Randomized Trials: An Overview of Methods and Results.

Commentary

• Rat Models of Diet-Induced Obesity and Metabolic Dysregulation: Current Trends, Shortcomings and Considerations for Future Research.
• The Mineralocorticoid Receptor in the Vasculature: Friend or Foe?
• Update on the Obesity Epidemic: Is the Sharp Rise of the Evil Empire Truly Levelling Off?
• ADHD in Obesity Clinics: Common, Often Missed, Highly Treatable.
• GIPR/GLP-1R Dual Agonist Therapies for Diabetes and Weight Loss—Chemistry, Physiology, and Clinical Applications.
• Scolding Instead of Helping with Chronic Illness.
• Video: How Digital Therapeutics are Changing Disease Management, Diabetes Care.
• "In this week’s Thought Leadership Roundtable, experts from CareSource, Indiana University School of Public Health-Bloomington, and Indiana Wesleyan University weigh in on the shortage of nurses and the epidemic of obesity in Indiana."

General

• The WFPB Diet Debate.
• Odi et Amo: The Arrival of Zero Acre Farms.
• Should Scientists Openly Debate Vaccine Policies?
• WHO Recommends Malaria Vaccine That Will Be Rolled Out Next Year.
• Determination of Polar Bear (Ursus maritimus) Individual Genotype and Sex Based on DNA Extracted from Paw-Prints in Snow.
• The Power of Dress.
• No bones about it: The effect of chewing on cognition in dogs.
• Adding robustness to rigor and reproducibility for the three Rs of improving translational medical research.

Video & Audio

• Future Event: Ask the Expert with John Shepherd: Research in Quantitative Imaging and Body Composition Analysis.

Announcements

• Dean of Indiana University School of Public Health-Bloomington Named Fellow of Sigma Xi Society.
• Jobs: NIDDK Recruiting for Director for Clinical Obesity Prevention and Treatment Program.
• Join Us Virtually at Noon (CT) on Tuesday, October 17, 2023, as We Welcome Dr. Megan Hays for Head over Meals: Weight Management Strategies from Behavioral Medicine.

Featured

• State-Specific Alterations in the Neural Computations Underlying Inhibitory Control in Women Remitted from Bulimia Nervosa.
• RCT: "Acute fasting reduces pain tolerance in the healthy participants, and this effect is independent of gender and attention or mood changes."
• In-Vivo Detection of White Adipose Tissue Browning: A Multimodality Imaging Approach.

Headline vs Study

• Headline: Sun Salute: Natural Light a Surprise Ally in Fighting Diabetes, Obesity.
• Headline: Daylight Exposure May Help Treat Type 2 Diabetes.
• Press Release: Daylight Rather Than Artificial Light Improves Blood Sugar Control and Nutrient Use in Type 2 Diabetes, Study Finds.
• Meeting Abstract: Natural Daylight Through Windows as Opposed to Artificial Lighting During Office Hours in 13 Type 2 Diabetes Patients over 4.5 Days. Treating Diabetes and Fighting Obesity Not Demonstrated.

Contrary or Null Findings

• RCT: "...a standalone social media intervention may have no effect on the influence of PA for Chinese postgraduates."
• RCT: "Level of processing did not affect food intake."
• RCT: "...contrary to our hypothesis, in a sample of healthy college students, an acute stressor decreases relative reinforcing value for food, with no difference between a low or high energy-dense food item."
• "The CRP-diabetes association could not be fully explained by obesity or hypertension."
• No Effect of Hunger on Attentional Capture by Food Cues: Two Replication Studies.
• "We found no evidence of mitochondrial genome adaptations to flight intensity."
• "There was no substantial deterioration in the healthiness of grocery purchases during COVID-19 lockdowns in Melbourne."
• "There is no evidence of a direct influence of certain nutrition or food intake on sleep."

Basic

• Vaccination Against Microbiota Motility Protects Mice from the Detrimental Impact of Dietary Emulsifier Consumption.
• Dietary Apigenin Relieves Body Weight and Glycolipid Metabolic Disturbance Via Pro-Browning of White Adipose Mediated by Autophagy Inhibition.
• Progression to Obesity: Variations in Patterns of Metabolic Fluxes, Fat Accumulation, and Gastrointestinal Responses.
• Genetic and Epigenetic Basis of Obesity-Induced Inflammation and Diabetes.
• Protective Effect of Probiotic Limosilactobacillus reuteri DSM17938 Against Western Diet-Induced Obesity and Associated Metabolic Alterations.

Scientific Rigor & Scholarly Dialogue

• Article: Effect Evaluation of Sahtak Bi Sahnak, a Lebanese Secondary School-Based Nutrition Intervention: A Cluster Randomised Trial.
• Letter: The Unclear Randomization Process Renders Conclusions Unverifiable and Ignoring Clustering in Statistical Analysis Renders Results Incorrect in “Effect Evaluation of Sahtak Bi Sahnak, a Lebanese Secondary School-Based Nutrition Intervention: A Cluster Randomised Trial”.
• Book Review: The Art and Science of Low Carbohydrate Living: An Expert Guide to Making the Life-Saving Benefits of Carbohydrate Restriction Sustainable and Enjoyable.

Clinical

• RCT: The Effects of Low-Fat Dairy Products Fortified with 1500 IU Vitamin D3 on Serum Liver Function Biomarkers in Adults with Abdominal Obesity.
• RCT: Late, but Not Early, Night Sleep Loss Compromises Neuroendocrine Appetite Regulation and the Desire for Food.
• RCT: Patient-Reported Outcomes, Weight Loss, and Remission of Type 2 Diabetes 3 Years After Gastric Bypass and Sleeve Gastrectomy (Oseberg).
• Systematic Review: The Effectiveness of Indigenous Knowledge-Based Lifestyle Interventions in Preventing Obesity and Type 2 Diabetes Mellitus in Indigenous Children in Canada.
• RCT: A Postpartum Weight Loss-Focused Stepped-Care Intervention in a Military Population.
• RCT: Dietary Treatment Postpartum in Women with Obesity Reduces Weight and Prevents Weight Gain.

Children and Adolescents

• Effects of Dietary Sugar Reduction on Biomarkers of Cardiometabolic Health in Latino Youth.
• Problematic Social Media Use Indirectly Influenced Overweight/Obesity Through Breakfast Skipping, Life Satisfaction, Family Communication, Self-Rated Health, and Physical Activity.
• Incidence of Diabetes Among Youth Before and During the COVID-19 Pandemic.
• RCT: A Community-Based Participatory Intervention to Prevent Obesity in New Immigrant Mother-Child Dyads.
• Development of a Checklist to Assess Potentially Effective Components in Combined Lifestyle Interventions for Children with Overweight or Obesity.

Surgery

• RCT: Roux-En-Y Gastric Bypass Improves Adiponectin to Leptin Ratio and Inflammatory Profile in Severely Obese Women with and Without Metabolic Syndrome.
• RCT: The Impact of Obesity on Vaginal Hysterectomy and Laparoscopically-Assisted Vaginal Hysterectomy Outcomes.
• What Is Best for Weight Loss? A Comparative Review of the Safety and Efficacy of Bariatric Surgery Versus Glucagon-Like Peptide-1 Analogue.

Drugs

• Meta-Analysis: The Benefit of Metformin in the Treatment of Pediatric Non-Alcoholic Fatty Liver Disease.
• Meta-Analysis: The Effects of Subcutaneous Tirzepatide on Obesity and Overweight.
• Meta-Analysis: Efficacy and Safety of Subcutaneous Semaglutide in Adults with Overweight or Obese.

Food & Diet

• Ethnic Differences in Eating Patterns and Their Associations with Obesity Among Adults in West China.
• Meta-Analysis: Comparative Effects of Nutraceuticals on Body Weight in Adults with Overweight or Obesity.
• RCT: Novel Multi-Ingredient Supplement Facilitates Weight Loss and Improves Body Composition in Individuals with Overweight or Obesity.

Caloric and Dietary Restriction

• Inhibition of Adipose Tissue Angiogenesis Prevents Rebound Weight Gain After Caloric Restriction in Mice Fed a High-Fat Diet.
• Time-Restricted Feeding Combined with Resistance Exercise Training Prevents Obesity and Improves Lipid Metabolism in the Liver of Mice Fed a High-Fat Diet.

Exercise & Physical Activity

• Walking Pace and Microvascular Complications Among Individuals with Type 2 Diabetes.
• Motor Competence and BMI in the Preschool Years: A Pooled Cross-Sectional Analysis of 5545 Children from Eight Countries.
• Best Practice Recommendations for Body Composition Considerations in Sport to Reduce Health and Performance Risks: A Critical Review, Original Survey and Expert Opinion by a Subgroup of the Ioc Consensus on Relative Energy Deficiency in Sport (REDS).
• Meta-Analysis: Effects of Different Exercise Modalities and Intensities on Body Composition in Children and Adolescents with Overweight or Obesity.
• RCT: Effects of a 12-Week Yoga Training Intervention on Blood Pressure and Body Composition in Female Adolescents with Obesity.

Economics & Sociology

• The Societal Costs and Health Impacts on Obesity of BMI Report Cards in US Schools.
• Obesity and Metabolic State are Associated with Increased Healthcare Resource and Medication Use and Costs.
• Global Human Obesity and Global Social Index: Relationship and Clustering.

Epidemiology

• The Longitudinal Effect of Ultra-Processed Food on the Development of Dyslipidemia/Obesity as Assessed by the NOVA System and Food Compass Score.
• Diminishing Benefits of Urban Living for Children and Adolescents’ Growth and Development.
• Body Shape Trajectories are Associated with Birth Weight, BMI and Sociodemographic Conditions in Participants of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
• General and Abdominal Obesity and Dietary Nutrient Intake Among University Students in Bangladesh: A Cross-Sectional Study Targeting Potential Risk Factors.
• The Association of BMI and Weight Waist Adjustment Index with Serum Ferritin in a National Study of US Adults.
• Factors Contributing to the Change in Overweight/Obesity Prevalence Among Indian Adults: A Multivariate Decomposition Analysis of Data from the National Family Health Surveys.
• Meta-Analysis: Waist to Height Ratio as a Simple Tool for Predicting Mortality.
• BMI and Incident Cardiometabolic Conditions in Relation to Obesity-Related Cancer Risk.

Psychology & Neuroscience

• Be More Mindful: Targeting Addictive Responses by Integrating Mindfulness with Cognitive Bias Modification or Cue Exposure Interventions.
• Variation in Executive Function Relates to BMI Increases in Youth Who Were Initially of a Healthy Weight in the ABCD Study.
• RCT: Effect of a Tobacco Cessation Intervention Incorporating Weight Management for Adults with Serious Mental Illness.
• Rise and Shine for Eating Right: The Link between Healthy Nutrition and Chronotype Among Young Adults.

Equity and Disparities

• Review: A Call to Reconceptualize Obesity Treatment in Service of Health Equity: Review of Evidence and Future Directions.
• Promoting Health Equity: Identifying Parent and Child Reactions to a Culturally-Grounded Obesity Prevention Program Specifically Designed for Black Girls Using Community-Engaged Research.
• Systematic Review: Racial Disparities in Selected Micronutrient Deficiencies After Bariatric Surgery.
• Temporal Trends in Obesity-Related Mortality Rates: An Analysis of Gender, Race/Ethnicity, and Geographic Disparities in the United States.

Stigma

• School Absenteeism and Impairment Associated with Weight Bullying.
• Physician Weight Influences Responses to a Public Health Message About the Genetics of Obesity.
• The Systematic Development of Guidance for Parents on Talking to Children of Primary School Age About Weight.

Policy Related

• Development and Validation of an Abbreviated Child and Adult Food Security Scale for Use in Clinical and Research Settings in the United States.
• Examining the Role and Strategies of Advocacy Coalitions in California’s Statewide Sugar-Sweetened Beverage Tax Debate (2001-2018).
• What Policies are There and What Policies are Missing? A Photovoice Study of Adolescents' Perspectives on Obesity-Prevention Policies in Their Local Environment.
• Co-Creating Obesity Prevention Policies with Youth: Policy Ideas Generated Through the CO-CREATE Project.
• Review: Tools and Resources Used to Support Implementation of Workplace Healthy Food and Drink Policies.

Intergenerational Effects

• Maternal High-Fat Diet Changes Breathing Pattern and Causes Excessive Sympathetic Discharge in Juvenile Offspring Rat.
• Meta-Analysis: BMI in Parents and Their Adult Offspring.

Ecology, Evolution, & Energetics

• Energetic Consequences of Prey Type in Little Penguins (Eudyptula minor).
• Limits to Sustained Energy Intake. XXXIII. Thyroid Hormones Play Important Roles in Milk Production but Do Not Define the Heat Dissipation Limit in Swiss Mice.
• Respirometry Reveals Major Lineage-Based Differences in the Energetics of Osmoregulation in Aquatic Invertebrates.

Methods

• Determining Classes of Food Items for Health Requirements and Nutrition Guidelines Using Gaussian Mixture Models.
• Daily Energy Intake in Adult Women: A Food-Recognition Mobile Application Compared to Doubly Labelled Water.

Commentary

• Here’s Why Obesity Grew So Quickly Worldwide, and Where That’s Starting to Change.
• Video: Late Night Workouts Could Cause Increased Risks.
• GLP-1 Drugs are Transforming Diabetes, Obesity and More. Could a Nobel Be Next?
• Mostly Fiddling While Earth Burns.
• Formula for Disaster: Exploring the Links between Federal Policies and the Infant Formula Crisis.
• Reminder: Semaglutide Is Not DIY Weight Loss.
• Understanding How Exercise Suppresses Appetite Could Pave the Way for New Obesity Drugs.
• Cost-Effectiveness of Bariatric Surgery: Addressing Severe Obesity and Comorbidities with RYGB and SG.

General

• The Secret to a Successful Career in Science—According to Magritte.
• The Impact of Cat Fostering on Older Adult Well-Being and Loneliness: A Feasibility Study.
• Is There a Single Essence of Aging?
• Computers are Amazing. But They Can't Distinguish between Correlation and Causation.
• The Food Is Medicine (FIM) Movement.
• Hemp-Fortified Foods & Beverages.
• Healthful Oils: Myths and Facts About Seed Oils.
• Costs of Parthenogenesis on Growth and Longevity in Ex Situ Zebra Sharks Stegostoma tigrinum.
• Chemically Induced Reprogramming to Reverse Cellular Aging.

Video & Audio

• PODCAST: Peter Attia on Lifespan, Healthspan, and Outlive.
• What You Need to Know About Weight-Loss Medications.

Announcements

• Obesity Week 2023.
• Food for Thought 2023: Rising to the challenge of obesity and diabetes.

Featured

• Can a Medicine Taste Too Good for Some? Genetic Variation and Sensory Perception of a Pediatric Formulation of Ibuprofen?
• "...the Tyrolean Iceman likely had ...carried risk alleles associated with male-pattern baldness, type 2 diabetes, and obesity-related metabolic syndrome."
• RCT: Caloric Restriction Intervention Alters Specific Circulating Biomarkers of the Senescence-Associated Secretome in Middle-Aged and Older Adults with Obesity and Prediabetes.
• Systematic Review: Health-Related Behaviors and Weight-Related Outcomes Within Sibling Pairs: A Systematic Review.

Headline vs Study

• Headline: Cutting Carbs Can Help Control Diabetes in Children, but Can Also Lead to Growth Decline, According to New Study.
• Press Release: American Academy of Pediatrics Issues Policy on Low-Carbohydrate Diets for Children and Adolescents with or at Risk of Diabetes.
• Clinical Report (Neither Study nor Policy): Low-Carbohydrate Diets in Children and Adolescents with or at Risk for Diabetes.

Contrary or Null Findings

• Meta-Analysis of RCTs: "Low-GI diet advice did not modulate the risk of GDM."
• "Contrary to previous findings, we found no evidence for an association between body dissatisfaction and attentional bias to thin bodies."
• "Contrary to our hypothesis, BMI is not associated with elevated bicarbonate levels..."
• "Contrary to our hypothesis, food insecurity had more deleterious effects on TL among participants with high social support than low social support."
• Meta-Analysis: Preserved Muscle Strength Despite Muscle Mass Loss After Bariatric Metabolic Surgery.
• Mammalian predator and prey responses to recreation and land use across multiple scales provide limited support for the human shield hypothesis. "Contrary to HSH predictions, carnivores did not avoid recreation and grizzly bear site use was positively associated."
• RCT: No Significant Effects of Short-Term Supervised Exercise Training on Liver Fat in Adolescents with Obesity.
• RCT: No Statistically Significant Influence of the Time of Day in the Effect of Caffeine on Maximal Fat Oxidation During Exercise in Women.

Basic

• EHD2 Regulates Plasma Membrane Integrity and Downstream Insulin Receptor Signalling Events.
• Reducing Gut Microbiome-Driven Adipose Tissue Inflammation Alleviates Metabolic Syndrome.
• Brown Adipocyte Mineralocorticoid Receptor Deficiency Impairs Metabolic Regulation in Diet-Induced Obese Mice.
• Adiponectin and Resistin Modulate the Progression of Alzheimer´s Disease in a Metabolic Syndrome Model.
• Global and Local Fat Effects on Bone Mass and Quality in Obesity.

Scientific Rigor & Scholarly Dialogue

• Letter: Relation of Fruit Juice with Adiposity and Diabetes Depends on How Fruit Juice Is Defined: A Re-Analysis of the EFSA Draft Scientific Opinion on the Tolerable Upper Intake Level for Dietary Sugars.
• Comment On: “Relation of Fruit Juice with Adiposity and Diabetes Depends on How Fruit Juice Is Defined: A Re-Analysis of the EFSA Draft Scientific Opinion on the Tolerable Upper Intake Level for Dietary Sugars” by Chen Et Al. 2023.
• Article: The Effects of Bright Light Treatment on Affective Symptoms in People with Dementia: A 24-Week Cluster Randomized Controlled Trial.
• Letter: Corrected Analysis of “The Effects of Bright Light Treatment on Affective Symptoms in People with Dementia: A 24-Week Cluster Randomized Controlled Trial” That Accounts for Clustering and Nesting Verifies Conclusions.

Clinical

• Review: Obesity Alters Immunopathology in Cancers and Inflammatory Diseases.
• Association of Weight and Shape Concern with Weight Change and Weight-Related Behaviors in Behavioral Weight Loss Treatment.
• Surrogate Adiposity Markers and Mortality.

Children and Adolescents

• Elucidating Pathways to Pediatric Obesity: A Study Evaluating Obesity Polygenic Risk Scores Related to Appetitive Traits in Children.
• Rapid Increases in BMI Waist to Height Ratio During Adolescence and Subsequent Neurobehavioral Deficits.
• Prevalence and Determinants of Overweight and Obesity Among Preschool-Aged Children from Migrant and Socioeconomically Disadvantaged Contexts in Montreal, Canada.
• Relationships of Pregnancy and Postpartum Diet Quality with Offspring Birth Weight and Weight Status Through 12 months.

Surgery

• Meta-Analysis: Endoscopic Therapies for Patients with Obesity.
• Osteoarthritis in Patients with Obesity: The Bariatric Surgery Impacts on Its Evolution.
• Vitamin D Concentration Changes After Bariatric Surgery.

Drugs

• Tirzepatide Reduces the Predicted Risk of Developing Type 2 Diabetes in People with Obesity or Overweight: Post Hoc Analysis of the SURMOUNT-1 Trial.
• Systematic Review: Impact of Estrogens on Resting Energy Expenditure.
• RCT: Retatrutide, a GIP, GLP-1 and Glucagon Receptor Agonist, for People with Type 2 Diabetes.

Food & Diet

• Scoping Review: Association of Plant-Based Diet Quality with Health Outcomes.
• Perspective: A Research Roadmap About Ultra-Processed Foods and Human Health for the US Food System: Proceedings from an Interdisciplinary, Multi-Stakeholder Workshop.
• Ultra-Processed Food Consumption and Mortality: Three Cohort Studies in the United States and United Kingdom.

Caloric and Dietary Restriction

• The Impact and Utility of Very Low-Calorie Diets: The Role of Exercise and Protein in Preserving Skeletal Muscle Mass.
• RCT: Caloric Restriction Intervention Alters Specific Circulating Biomarkers of the Senescence-Associated Secretome in Middle-Aged and Older Adults with Obesity and Prediabetes in an 18-Week RCT.
• Preprint: Caloric Restriction Promotes Beta Cell Longevity and Delays Aging and Senescence Signatures.

Exercise & Physical Activity

• Both Moderate- and High-Intensity Exercise Training Increase Intramyocellular Lipid Droplet Abundance and Modify Myocellular Distribution in Adults with Obesity.
• Morning Exercise Was Not Quite as Effective as Evening Exercise: Temporal Optimization of Exercise to Lower Fasting Glucose Levels.
• RCT: Effects of Short-Term Supervised Exercise Training on Liver Fat in Adolescents with Obesity.
• Preprint: Stepping Up for All of Us: Data from the All of Us Research Program Reinforces Existence of Activity Inequality in the United States.

Economics & Sociology

• Meta-Analysis: Interventions That Target the Intersection of Body Image and Movement Among Girls and Women.
• Dissertation: Towards a Biobehavioral and Social-Structural Model of Inflammation and Executive Function in Pediatric Obesity.

Epidemiology

• Greater Male Variability in Daily Energy Expenditure Develops Through Puberty.
• Mediating Processes Underlying the Associations between Maternal Obesity and the Likelihood of Cesarean Birth.
• Association of Fat Mass and Fat-Free Mass with All-Cause and Cause-Specific Mortality in Asian Individuals: A Prospective Cohort Study.
• Maternal Overweight and Obesity Modify the Association of Serum Fibroblast Growth Factor 21 Levels with Gestational Diabetes Mellitus: A Nested Case-Control Study.
• Meta-Analysis: The Prevalence of Metabolic Syndrome and Its Components in Firefighters.
• Dissertation: Body Size over the Life Course and the Risk of Colorectal Cancer in Postmenopausal Women.

Psychology & Neuroscience

• Using Public Datasets to Understand the Psychological Correlates of Smoking, Alcohol Consumption, and Obesity: A Country-Level Analysis.
• The Iterative Mindset Method: A Neuroscientific Theoretical Approach for Sustainable Behavior Change and Weight-Loss in Digital Medicine.
• The Role of Interoception in Age-Related Obesity: A Structural Equation Modelling Study.
• Associations Among Eating Behaviors, Food Security Status, and Dietary Intake During Pregnancy.

Equity and Disparities

• Systematic Review: Lack of Consideration of Socioeconomic Factors in Transition Programme of Adolescents with Type 1 Diabetes.
• Physical Inactivity and Obesity in the United States Through the Lens of the 2012 and 2016 Presidential Elections.
• Health Equity in Action: Using Community-Engaged Research to Update an Intervention Promoting a Healthy Home Food Environment to Black/African American Families.

Ethics

• Should Pharmaceuticals Be Used as Weight Loss Interventions for Adolescents Classified as Obese by BMI?
• The Ethics of Using BMI in In-Vitro Fertilization Risk Assessment.

Stigma

• Consensus: "Anti-obesity medications" or "medications to treat obesity" instead of "weight loss drugs" - why language matters?
• Weight Stigma from Romantic Partners: Its Relations with Maladaptive and Adaptive Coping and Depressive Symptoms.
• Mechanisms of Stigmatization in Family-Based Prevention and Treatment of Childhood Overweight and Obesity.

Policy Related

• Review: How Could Taxes on Sugary Drinks and Foods Help Reduce the Burden of Type 2 Diabetes?
• Which Government Policies to Create Healthy Diets from Sustainable Food Systems Have the Potential to Simultaneously Address Undernutrition, Obesity and Environmental Sustainability? Results of an Evidence Review and International Expert Consultation.
• Systematic Review: Policy, Systems, and Environmental Changes in Child Nutrition Programs: A Systematic Literature Review.
• Federal Nutrition Assistance for Young Children: Under-Utilized and Unequally Accessed.
• RCT: Effects of 4 Interpretive Front-Of-Package Labeling Systems on Hypothetical Beverage and Snack Selections.

Intergenerational Effects

• The Influence of Dietary Diversity on Anthropometric Status Among Young Children Ages 12 and 24 Months in Wuhan, China.
• High Prevalence of Medical Conditions and Unhealthy Lifestyle Behaviours in Women with PCOS During Preconception: Findings from the Australian Longitudinal Study on Women’s Health.
• A Pre-Conception Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks: The NDPP-NextGen Trial Protocol.

Ecology, Evolution, & Energetics

• Mitochondrial Dysfunction in PCOS: Insights Into Reproductive Organ Pathophysiology.
• Hypothalamic Astrocytic-BMAL1 Regulates Energy Homeostasis in a Sex-Dependent Manner.
• Nonequilibrium Thermodynamics and Mitochondrial Protein Content Predict Insulin Sensitivity and Fuel Selection During Exercise in Human Skeletal Muscle.

Methods

• Juvenile Body Mass Estimation from the Femur Using Postmortem Computed Tomography Data.
• Comparison of Artificial Intelligence and Eyeball Method in the Detection of Fatty Liver Disease.
• Design, Analysis, and Interpretation of Treatment Response Heterogeneity in Personalized Nutrition and Obesity Treatment Research.
• Objective Determination of Eating Occasion Timing (OREO): Combining Self-Report, Wrist Motion, and Continuous Glucose Monitoring to Detect Eating Occasions in Adults with Pre-Diabetes and Obesity.

Commentary

• The Long Arc of Obesity Prevalence.
• The Failure of Gene-Centrism.
• Global Obesity Fight Hindered: Need for Deeper Insight Grows.
• Editorial: Neuroplasticity: The Critical Issue for Alzheimer's Disease and Links to Obesity and Depression.
• US FDA Panel Votes Against Diabetes Implant Due to Safety Concerns.
• Using Conspiracy Theories and Fear for Public Health.
• Decoding the Mechanisms Behind Early Weaning–Driven Obesity and the Leucine “Solution”.
• Osteosarcopenic Obesity: A Triple Threat for Older Adults?

General

• Preprint: Taste Shaped the Use of Botanical Drugs.
• Letter: Should Patient Enrollment Criteria for Anti-VEGF Phase III Trials Be Reconsidered?
• Not All Very-Low-Carbohydrate Diets are Created Equal.
• The Application of Digital Technologies and Artificial Intelligence in Healthcare: An Overview on Nutrition Assessment.
• Anxiolytic Effects of Endocannabinoid Enhancing Compounds: A Systematic Review and Meta-Analysis.
• Uniformity in Dress: A Worldwide Cross-Cultural Comparison.
• "Our results point to an expansion of time spent frail among older Swedish adults over time."
• Neural Correlates of Naturalistic Single-Trial Appetitive Conditioning.
• Evaluation of an Experiment to Increase Availability of Healthier Snack Foods in Vending Machines Situated Within English Sports Facilities.

Video & Audio

• Obesity in America: Exploring Anti-Obesity Medications and Addressing Policy Challenges.

Announcements

• IU Faculty and Board Member Featured in Nutritional Outlook’s Women in Nutraceuticals Roundtable: Women in Nutrition Education.
• IU Bloomington Named Among the Nation’s Most LGBTQ-Friendly Campuses.
• Webinar Registration: Center for Childhood Obesity Prevention - Say What You'll Do and Do What You Say: Principles of Reproducible Research. October 13, 2023.

Featured

• Questioning the Foundations of the Gut Microbiota and Obesity.
• Cold Comfort: Metabolic Rate and Tolerance to Low Temperatures Predict Latitudinal Distribution in Ants.
• RCT: ‘Tracking Together’-Simultaneous Use of Human and Dog Activity Trackers.
• The Origins of the Obesity Epidemic May Be Further Back Than We Thought.

Headline vs Study

• Headline: A New Study Shows That Extreme Diets are Doing More Harm Than Good.
• Press Release: Extreme Dietary Habits for Carbohydrates and Fats Affect Life Expectancy.
• Study: Associations between Seemingly Arbitrary Bins of Self-Reported Estimates of Carbohydrate or Fat Intake and Mortality.

Contrary or Null Findings

• Failure to Replicate the Diabetes Alleviating Effect of a Maternal Gluten-Free Diet in Non-Obese Diabetic Mice.
• Study Finds No Significant Link between EGFR and DME in Latino Patients.
• Prolactin Does Not Seem to Mediate the Improvement on Insulin Resistance Markers and Blood Glucose Levels Related to Breastfeeding.
• Metabolic Rate Does Not Explain Performance on a Short-Term Memory Task or Personality Traits in Juvenile Chickens (Gallus gallus domesticus).
• "We found no evidence of an association between determinants and the number of PA programs and activities implemented."
• "In conclusion, routinely supplementing older adults, who are largely vitamin D replete, with monthly doses of vitamin D is unlikely to influence telomere length."
• RCT: "There is no evidence that lifestyle or metformin improves live birth, and adequately powered clinical trials are required."
• RCT: "A 750-mg daily supplementation of celery powder for 12 weeks did not improve the cardiometabolic factors of patients with T2DM."

Basic

• Thesis: A Novel Genetic Method to Study D-2-Hydroxyglutarate (D-2HG) Metabolism.
• Effect of Simultaneous Intake of Rare Sugars Allitol and D-Allulose on Intra-Abdominal Fat Accumulation in Rats.
• Single-Nucleus RNA-Sequencing Reveals NRF1/NFE2L1 as a Key Factor Determining the Thermogenesis and Cellular Heterogeneity and Dynamics of Brown Adipose Tissues in Mice.
• Pancreastatin Inhibitor PSTi8 Ameliorates Insulin Resistance by Decreasing Fat Accumulation and Oxidative Stress in High-Fat Diet-Fed Mice.
• Energy Expenditure Deficits Drive Obesity in a Mouse Model of Alström Syndrome.

Scientific Rigor & Scholarly Dialogue

• Meta-Analysis: Bias in the Measurement of the Outcome Is Associated with Effect Sizes in Randomised Clinical Trials on Exercise Therapy for Chronic Low Back Pain. (pdf)
• Letter: Ignoring Clustering and Nesting Effects are Invalid Analysis Choices in a Trial with Clustered Data in Trials Testing Causal Effects. Re: “Impact of a Montessori-Based Nutrition Program on Children's Knowledge and Eating Behaviors”.
• Reply: Re: “Ignoring Clustering and Nesting Effects are Invalid Analysis Choices in a Trial with Clustered Data in Trials Testing Causal Effects”.

Clinical

• RCT: Can Smartphone-Based Response Inhibition Training Elicit Sustained Changes in Appetite, Preference, and Cravings for Energy-Dense Foods?
• RCT: Effectiveness of the Telemedical Lifestyle Intervention Program TeLIPro for Improvement of HbA1c in Type 2 Diabetes.
• RCT: Adherence to a Mediterranean Diet May Improve Serum Adiponectin in Adults with Non-Alcoholic Fatty Liver Disease.
• RCT: Dietary Sulfur Amino Acid Restriction in Humans with Overweight and Obesity.

Children and Adolescents

• The Global Observatory for Physical Education (GoPE!): Monitoring Physical Education and Physical Activity in Children and Adolescents Worldwide.
• Dietary Protein in Early Pregnancy and Gestational Diabetes Mellitus. (pdf)
• Body Composition Assessment in the Infant. (pdf)
• Low-Carbohydrate Diets in Children and Adolescents with or at Risk for Diabetes.
• Effects of Exercise on Whole-Blood Transcriptome Profile in Children with Overweight/Obesity.

Surgery

• Editorial: The Impact of Microbially Modified Metabolites Associated with Obesity and Bariatric Surgery on Anti-Tumor Immunity.
• Long-Term Incidence of Haematological Cancer After Bariatric Surgery or Usual Care in the Swedish Obese Subjects Study.
• Editorial: Walking Through the Tracts in the Era of Bariatric Surgery: Obesity and White Matter Integrity.

Drugs

• Review: Upcoming and Currently Available Anti-Obesity Drugs in Europe.
• Anti-Obesity Drugs: From Previous Disappointments to New Hopes.
• Dipterocarpus tuberculatus as a Promising Anti-Obesity Treatment in Lep Knockout Mice.

Food & Diet

• Chronotype, Unhealthy Lifestyle, and Diabetes Risk in Middle-Aged U.S. Women.
• RCT: Almonds vs Carbohydrate Snacks in an Energy-Restricted Diet: Weight and Cardiometabolic Outcomes.
• Snack Quality and Snack Timing are Associated with Cardiometabolic Blood Markers.

Caloric and Dietary Restriction

• Geroprotective Interventions Converge on Gene Expression Programs of Reduced Inflammation and Restored Fatty Acid Metabolism.
• Regulation of IGF1R by MicroRNA-15b Contributes to the Anticancer Effects of Calorie Restriction in a Murine C3-TAg Model of Triple-Negative Breast Cancer.

Exercise & Physical Activity

• Assessing the Effect of Regular Swimming Exercise on the Micro- and Macrovascular Physiology of Older Adults.
• Gender-Specific Associations between Abdominal Adipose Mass and Bone Mineral Density in the Middle-Aged US Population.
• Symposium: School-Based Interventions to Promote Physical Activity Amongst Children and Adolescents.

Economics & Sociology

• Impact of Social Connectedness on Weight Loss Outcomes in an Online Program.
• Interpersonal Discrimination, Neighborhood Inequities, and Children's BMI.

Epidemiology

• BMI Categories Across Different Living Arrangements.
• Emergence of the Obesity Epidemic Preceding the Presumed Obesogenic Transformation of the Society.
• Real-World Costs of Obesity-Related Complications over Eight Years: A US Study in 28,500 Individuals.
• Higher BMI Is Associated with Increased Arterial Stiffness Prior to Target Organ Damage.
• Racial and Ethnic Inequities in Development of Type 2 Diabetes After Gestational Diabetes Mellitus.
• Prevalence and Factors Associated with Undernutrition and Overnutrition Among Ever-Married Adolescent Girls in Bangladesh: An Analysis of National Surveys from 2004 to 2017.

Psychology & Neuroscience

• The Relationship of Food Addiction with Binge Eating Disorder and Obesity.
• Working Memory Gating in Obesity: Insights from a FMRI Study.

Equity and Disparities

• Mediation of the Association between Disadvantaged Neighborhoods and Cortical Microstructure by BMI.
• School-Based Health Centers, Access to Care, and Income-Based Disparities.

Stigma

• Barriers and Facilitators for Sustainable Weight Loss in the Pre-Conception Period Among Danish Women with Overweight or Obesity.
• RCT: A Short-Form Drama Series Created for the Digital Media Environment: Exploring Effects on Girls’ Body Satisfaction, Acceptance of Appearance Diversity, and Appearance-Related Internalised Racism.

Policy Related

• Public Support for Obesity Prevention Policies in Western Australia from 2012 to 2020.
• Opportunities in the Extended Day: Approaches for Promoting Physical Activity and Healthy Eating During Out-Of-School Time.
• Review: A Scoping Review of the Impact of Food Policy Groups on Local Food Systems in High-Income Countries.
• A Multi-Country Comparison of Jurisdictions with and Without Mandatory Nutrition Labelling Policies in Restaurants: Analysis of Behaviours Associated with Menu Labelling in the 2019 International Food Policy Study.
• Dissertation: Military Readiness Implications of the United States Obesity Epidemic.
• Review: The Makings of a Maternal Obesity Epidemic.
• "The analysis reveals a long-term decline in the income floor, whereas adding SNAP to income and correcting for underreporting has reversed this decline and lifted the income floor by more than 75% on average between 2011 and 2016."

Intergenerational Effects

• Effect of Childbearing-Age Women’s Family Status on the Health Status of Three Generations: Evidence from China.
• Editorial: Exercised Breastmilk: A Kick-Start to Prevent Childhood Obesity?
• Does Grandchild Care Intention, Intergenerational Support Have an Impact on the Health of Older Adults in China?

Ecology, Evolution, & Energetics

• Preprint: Microbes with Higher Metabolic Independence are Enriched in Human Gut Microbiomes Under Stress.
• Parasitism Does Not Reduce Thermal Limits in the Intermediate Host of a Bopyrid Isopod.

Methods

• Abstract: Weighted Mean Difference Statistics for Paired Data in the Presence of Missing Values.
• Machine Learning Accurately Predicts Food Exchange List and the Exchangeable Portion.

Mathematical and Quantitative

• Preprint: The Genetic and Dietary Landscape of the Muscle Insulin Signalling Network.

Commentary

• How’s That Microbiome Working for You in Obesity?
• Malnutrition Early in Life Sets Stage for Poor Growth and Death: Three Papers Explore This Devastating Reality.
• Is Coconut Oil Healthy? Mouse Study Finds It May Alter Metabolism and Cause Obesity.
• Evening Chronotype Tied to Unhealthy Behaviors, Diabetes Risk.
• Obesity Surgery Devices Market to Witness Robust Growth.
• How Can Low Calorie Diets and Intermittent Fasting Benefit Patients with Type 2 Diabetes?
• Ultra-Processed, Ultra-Worried, Ultra-Tricky Guidance.
• Commentary on Impact of BMI on Surgical Case Durations in an Academic Medical Center.

General

• Impacts of a Severe Hailstorm on a White-Tailed Deer Population in East-Central Alabama.
• Publication Bias Is Corrupting the Scientific Record, New Evidence from PM&R.
• Most Cochrane Systematic Reviews and Protocols Did Not Adhere to the Cochrane's Risk of Bias 2.0 Tool.
• Experimental and Meta-Analytic Evidence That Source Variability of Misinformation Does Not Increase Eyewitness Suggestibility Independently of Repetition of Misinformation.
• Primate Richness and Abundance Is Driven by Both Forest Structure and Conservation Scenario in Costa Rica.
• Characterization of Fetal Microchimeric Immune Cells in Mouse Maternal Hearts During Physiologic and Pathologic Pregnancies.
• Socio-Sexual Exposure Has Opposing Effects on Male and Female Actuarial Senescence in the Fruit Fly Drosophila melanogaster.
• Practical Recommendations to Improve Retention of Underrepresented Minorities in Science and Medicine: An Early Career Perspective.

Announcements

• September Is Hunger Action Month.
• The Cardiorenal Connection: Diagnosis & Treatment of CKD Associated with T2D.