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Contrary or Null Findings
- RCT: Early Initiation of Metformin Did Not Significantly Reduce Insulin Initiation or Improve Fasting Hyperglycemia at Gestation Weeks 32 or 38.
- "Mitochondrial genes in every study species exhibited evidence of purifying selection, but the strength of selection was greater in short-distance migrants, contrary to our predictions."
- "Contrary to our hypothesis, low BMI had no impact on patient survival" in patients with familial dysautonomia.
- "Although temperatures increased at Mývatn over this period, there was only a slight (non-significant) decrease in midge adult body size, contrary to theoretical expectations."
- "Contrary to our hypothesis, when consumed in combination, evening alcohol consumption interacted with ongoing caffeine consumption such that alcohol partially mitigated the impairments in sleep quantity associated with caffeine (p = 0.032)."
- "Sub-effective doses of glucose plus Ad administered simultaneously to Ad-deficient mice increased contextual fear memory, contrary to independent sub-effective doses" in mice.
- "Contrary to some published trials, our meta-analysis concludes that the use of probiotics in patients with SAP is not effective in reducing the mortality rate, septic complications, and need for operation."
- "Contrary to expectations, higher VAI [visceral adiposity index] levels were associated with higher overall cognitive scores and improved episodic memory scores, while no significant effect was observed on mental status."
Basic
Scientific Rigor & Scholarly Dialogue
Clinical
Children and Adolescents
Surgery
Drugs
Food & Diet
Caloric and Dietary Restriction
Exercise & Physical Activity
Economics & Sociology
Epidemiology
Psychology & Neuroscience
Equity and Disparities
Ethics
Stigma
Policy Related
Intergenerational Effects
Ecology, Evolution, & Energetics
Methods
Mathematical and Quantitative
Commentary
General
Video & Audio
Announcements
Featured
Headline vs Study
Contrary or Null Findings
Basic
Scientific Rigor & Scholarly Dialogue
Clinical
Children and Adolescents
Surgery
Drugs
Food & Diet
Caloric and Dietary Restriction
Exercise & Physical Activity
Economics & Sociology
Epidemiology
Psychology & Neuroscience
Equity and Disparities
Stigma
Policy Related
Intergenerational Effects
Ecology, Evolution, & Energetics
Methods
Commentary
General
Announcements
Featured
Headline vs Study
Contrary or Null Findings
Basic
Scientific Rigor & Scholarly Dialogue
Clinical
Children and Adolescents
Surgery
Drugs
Food & Diet
Caloric and Dietary Restriction
Exercise & Physical Activity
Economics & Sociology
Epidemiology
Psychology & Neuroscience
Equity and Disparities
Ethics
Stigma
Policy Related
Intergenerational Effects
Ecology, Evolution, & Energetics
Methods
Commentary
General
Video & Audio
Announcements
Featured
Headline vs Study
Contrary or Null Findings
- MTORC1 Signaling in AgRP Neurons Is Not Required to Induce Major Neuroendocrine Adaptations to Food Restriction.
- Gut Transplants from Bees Fed an Antipathogenic Pollen Diet Do Not Confer Pathogen Resistance to Recipients.
- Meta-Analysis of RCTs: "There was no evidence to suggest that commercial exergames are more beneficial for improving cognitive flexibility, inhibitory control, or working memory than conventional exercises."
- In mongooses, "Furthermore, the accuracy of their carer predicted future survival, but not weight gain of the pups and the effect was contrary to expected, with pups that were cared for by less accurate individuals being more likely to survive to adulthood."
- "...no evidence that overall CDS (cognitive disengagement syndrome) symptoms or ADHD symptoms (overall and subdomain) predicted child BMI."
- "Among non-diabetic adults, environmental exposures were not consistently associated with HbA1c."
- RCT: "The intervention did not result in improved diet quality or cardiovascular health as measured by HEI-2015 or LS7" in Evaluation of the SuperShelf Intervention in Choice-Based Food Pantries.
- RCT: "Our results did not show significant differences in body weight, blood sugar, fasting insulin, or lipid profiles between TRE (time restricted eating) plus BE (behavioral economic) interventions, TRE alone, and usual care groups" in Patients with Impaired Fasting Glucose.
Basic
Scientific Rigor & Scholarly Dialogue
Clinical
Children and Adolescents
Surgery
Drugs
Food & Diet
Caloric and Dietary Restriction
Exercise & Physical Activity
Economics & Sociology
Epidemiology
Psychology & Neuroscience
Equity and Disparities
Stigma
Policy Related
Intergenerational Effects
Ecology, Evolution, & Energetics
Commentary
General
Video & Audio
Announcements
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