Obesity and Energetics Offerings

Featured

• The Sting of Sizeism in the Scientific Workplace.
• Sex Differences in the Relationships between Body Composition, Fat Distribution, and Mitochondrial Energy Metabolism: A Pilot Study.
• Dietary Oleamide Attenuates Obesity Induced by Housing Mice in Small Cages.
• Anopheles stephensi Feeding, Flight Behavior, and Infection with Malaria Parasites are Altered by Ingestion of Serotonin.
• Serotonin and Dopamine Modulate Aging in Response to Food Odor and Availability.

Headline vs Study

• Headline: To Lose Weight and Keep It Off, Study Finds Lifestyle Changes and Medications Can Be Crucial.
• Meeting Abstract: Abstract OR10 - A "retrospective observational study of adults 18-75 years treated for overweight/obesity at a tertiary academic weight management center". Causation (and "Cruciality") Not Established.

Contrary or Null Findings

• Meta-Analysis: "when compared with in-person interventions, technology-based interventions were found to lead in significantly higher weight regain".
• Consumption of Low Dose Fucoxanthin Does Not Prevent Hepatic and Adipose Inflammation and Fibrosis in Mouse Models of Diet-Induced Obesity.
• Addition of Prebiotics to the Ketogenic Diet Improves Metabolic Profile but Does Not Affect Seizures in a Rodent Model of Infantile Spasms Syndrome.
• RCT: Weight-Loss Induced by Carbohydrate Restriction Does Not Negatively Affect Health-Related Quality of Life and Cognition in People with Type 2 Diabetes.
• Neuropeptide Neuromedin B Does Not Alter Body Weight and Glucose Homeostasis nor Does It Act as an Insulin-Releasing Peptide [in Mice].
• Living Alone Is Not Associated with Cardiovascular Events and Hypoglycemia in Patients with Type 2 Diabetes Mellitus.
• Treatment of Hyperglycemia Not Associated with NAFLD Improvement in Children with Type 2 Diabetes Mellitus.
• RCT: Omega-3 Index Is Associated with Cardiometabolic Risk Factors but Is Not Improved by Walnut Intake in Free Living Elderly.

Basic

• SARS-CoV-2 Infection Impairs the Insulin/IGF Signaling Pathway in the Lung, Liver, Adipose Tissue, and Pancreatic Cells Via IRF1.
• Emerging Central and Peripheral Actions of Spexin in Feeding Behavior, Leptin Resistance and Obesity.
• Hypothalamic NPY-Y1R Interacts with Gonadal Hormones in Protecting Female Mice Against Obesity and Neuroinflammation.
• An Exercise-Inducible Metabolite That Suppresses Feeding and Obesity.
• Functional and Morphologic Dysfunctions in the Airways of Rats Submitted to an Experimental Model of Obesity-Exacerbated Asthma.
• Intermittent Sucrose Solution Intake and Its Schedule of Access Modulate Energy Intake and Weight Gain in Response to Chronic Variable Stress in Mice.

Scientific Rigor & Scholarly Dialogue

• Letter: Energy Balance Model Vs. The Carbohydrate Insulin Model.
• Letter: Leaving Energy Balance Behind.
• Letter: Clarification on Our Critique of the Energy Balance Hypothesis of Obesity.
• Response: Reply to Taubes, Friedman, and Torres-Carot et al.
• Perspective: Does the Concept of “Ultra-Processed Foods” Help Inform Dietary Guidelines, Beyond Conventional Classification Systems? YES.
• Perspective: Does the Concept of “Ultra-Processed Foods” Help Inform Dietary Guidelines, Beyond Conventional Classification Systems? NO.
• Letter Preprint: Effects of Being Overweight on Mortality are Unclear Given Multiple Methodological Problems.

Clinical

• RCT: Increased Weight Loading Reduces Body Weight and Body Fat in Subjects with Obesity.
• The Feasibility and User-Experience of a Digital Health Intervention Designed to Prevent Weight Gain in New Kidney Transplant Recipients.
• Meta-Analysis: Effectiveness of Prone Position in Acute Respiratory Distress Syndrome and Moderating Factors of Obesity Class and Treatment Durations for COVID-19 Patients.
• Intermittent Fasting Two Days Versus One Day Per Week, Matched for Total Energy Intake and Expenditure, Increases Weight Loss in Men and Women with Overweight/Obesity.
• An Atypical Form of Diabetes Among Individuals with Low BMI.
• Exercise and Nutrition Strategies for Combating Sarcopenia and Type 2 Diabetes Mellitus in Older Adults.

Children and Adolescents

• Obesity in Adolescents Associated with Vascular Aging – a Study Using Ultra-High-Resolution Ultrasound.
• The Mediating Effect of Sleep Duration on the Association between Food Insecurity and Childhood Obesity.
• Impacts of an Early Childhood Obesity Prevention Program in Mexico.

Surgery

• Rhabdomyolysis as a Rare Complication of Bariatric Surgery.
• Meta-Analysis: Effect of Physical Exercise on Muscle Strength in Adults Following Bariatric Surgery.
• Association of Bariatric Surgery with Cancer Risk and Mortality in Adults with Obesity.
• Review: Differences between the 2016 and 2022 Editions of the Enhanced Recovery After Bariatric Surgery (ERABS) Guidelines.
• Obesity Pillars Roundtable: Metabolic and Bariatric Surgery in Children and Adolescents.

Drugs

• Medical Nutritional Therapy on Schizophrenic Patient with Grade 2 Obesity and Continued Antipsychotic Drug Use.
• A GLP-1/Glucagon (GCG)/CCK2 Receptors Tri-Agonist Provides New Therapy for Obesity and Diabetes.
• Meta-Analysis: Efficacy and Safety of Once-Weekly Semaglutide in Adults with Overweight or Obesity.
• Untapped Pharmaceutical Potential of 4,5,4′-Trihydroxy-3,3′-Dimethoxybibenzyl for Regulating Obesity: A Cell-Based Study with a Focus on Terminal Differentiation in Adipogenesis.
• Long-term Weight Loss Maintenance with Obesity Pharmacotherapy: A Retrospective Cohort Study.

Food & Diet

• Meta-Analysis: A Single High-Fat Meal Adversely Affects Postprandial Endothelial Function.
• Systematic Review: Nutri-Epigenetic Effects of Phenolic Compounds from Extra Virgin Olive Oil.
• Contributing Factors of Sugar-Sweetened Beverage Intake in the Latinx Population: A Narrative Review Using the Social-Ecological Model.
• Consumption of Takeaway and Delivery Meals Is Associated with Increased BMI and Percent Fat Among UK Biobank Participants.
• Systematic Review: Factors Influencing Independent Older Adults (Un)healthy Food Choices:.
• Meta-Analysis: Consumption of Whole Grains and Risk of Type 2 Diabetes.
• RCT: Avocado Consumption for 12 Weeks and Cardio-Metabolic Risk Factors in Adults with Overweight or Obesity and Insulin Resistance.
• Meta-Analysis: Effects of Vegan Diets on Cardiometabolic Health.

Caloric and Dietary Restriction

• Dietary Restriction Ameliorates TBI-Induced Phenotypes in Drosophila Melanogaster.
• Longitudinal Effects of Growth Restriction on the Murine Gut Microbiome and Metabolome.

Exercise & Physical Activity

• The Effects of Reconditioning Exercises Following Prolonged Bed Rest on Lumbopelvic Muscle Volume and Accumulation of Paraspinal Muscle Fat.
• Meta-Analysis: Effects of Protein Supplementation Associated with Resistance Training on Body Composition and Muscle Strength in Older Adults.
• Examining the State, Quality and Strength of the Evidence in the Research on Built Environments and Physical Activity Among Children and Youth: An Overview of Reviews from High Income Countries.

Economics & Sociology

• The Relationships between Socioeconomic Status, Dietary Knowledge and Patterns, and Physical Activity with Adiposity in Urban South African Women.
• Community Food Security: The Multi-Level Association between Social Capital, Economic Capital, and Diet Quality.
• Revisiting the Obesity Paradox in Health Care Expenditures Among Adults with Diabetes.

Epidemiology

• Meta-Analysis: The Association between Workplace Built Environment and Metabolic Health.
• Metabolically Healthy Obesity: Inflammatory Biomarkers and Adipokines in Elderly Population.
• A Lifecourse Mendelian Randomization Study Highlights the Long-Term Influence of Childhood Body Size on Later Life Heart Structure.
• Robust Variation in Infant Gut Microbiome Assembly Across a Spectrum of Lifestyles.
• Sibling Group Size and BMI over the Life Course: Evidence from Four British Cohort Studies.
• Meta-Analysis: Prevalence of Overweight and Obesity in Nigeria.
• Changes in Anthropometric Indicators and Gait Speed in Older Adults.

Psychology & Neuroscience

• Pathophysiological Mechanisms Explaining the Association between Low Skeletal Muscle Mass and Cognitive Function.
• Chronic Experience with Unpredictable Food Availability Promotes Food Reward, Overeating, and Weight Gain in a Novel Animal Model of Food Insecurity.
• White Matter Fiber-Specific Degeneration in Older Adults with Metabolic Syndrome.
• Long Term High Fat Diet Induces Metabolic Disorders and Aggravates Behavioral Disorders and Cognitive Deficits in MAPT P301L Transgenic Mice.

Equity and Disparities

• Trends and Disparities in Adult BMI Across the 47 Prefectures of Japan, 1975–2018.
• Using Syndemic Theory to Understand Food Insecurity and Diet-Related Chronic Diseases.

Stigma

• Does Obesity Rule Out Happiness? Preschool Children’s Perceptions of Beauty-Related Happiness.
• Say What You Mean, Mean What You Say: The Importance of Language in the Treatment of Obesity.

Policy Related

• Obesity Prevention Across the US: A Review of State-Level Policies from 2009-2019.
• The Nutrition Transition, Food Retail Transformations, and Policy Responses to Overnutrition in the East Asia Region: A Descriptive Review.
• Nutrition Policies in Germany: A Systematic Assessment with the Food Environment Policy Index.
• Benchmarking for Accountability on Obesity Prevention: Evaluation of the Healthy Food Environment Policy Index (Food-EPI) in Australia (2016–2020).

Intergenerational Effects

• Normalization of Maternal Adiponectin in Obese Pregnant Mice Prevents Programming of Impaired Glucose Metabolism in Adult Offspring.
• Eating Competence Among Caregivers of Toddlers: Associations with Caregiver and Child Overweight/Obesity.
• Associations of Cord Blood Lipids with Childhood Adiposity at the Age of Three Years.
• Effect of a Maternal High Fat Diet with Vegetable Substitution on Fetal Brain Transcriptome.

Ecology, Evolution, & Energetics

• Darwinian Applications to Nutrition: The Value of Evolutionary Insights to Teachers and Students.
• Skeletal Muscle Plasticity and Thermogenesis: Insights from Sea Otters.

Methods

• Agreement and Precision of Deuterium Dilution for Total Body Water and Multicompartment Body Composition Assessment in Collegiate Athletes.
• Estimating National and Subnational Nutrient Intake Distributions of Global Diets.

Mathematical and Quantitative

• A Theoretical Analysis of a Model for Diabesity Dynamics. (pdf)
• A comprehensive dynamic model of the adipocyte.

Commentary

• A Darkened Neck Could Be a Sign for Type 2 Diabetes. But Texas Screenings Have Slowed.
• Diabetes Drug Helps Patients Lose Never-Before-Seen Amounts of Weight, New Study Shows.
• Obesity: Policy and Practice Recommendations for High-Risk Populations Influenced by the COVID-19 Pandemic.
• Changes are Coming to School Meals Nationwide – an Expert in Food Policy Explains.
• Weight Loss Tied to a Dramatic Drop in Cancer Risk, New Study Shows.
• 5 Nutrition and Food Safety Pregnancy Myths.
• Muddled Thinking and Silly Arguments About BMI.
• Are Ultra-Processed Foods Harmful? Experts Weigh the Evidence.

General

• Methods Matter: P-Hacking and Publication Bias in Causal Analysis in Economics: Comment.
• Trait Energy and Fatigue May Be Connected to Gut Bacteria Among Young Physically Active Adults: An Exploratory Study.
• Importance of Treating Smoking in Conjunction with Mental Health.
• The Replication Crisis and the Problem with Basic Science.
• Palatal Morphology Predicts the Paleobiology of Early Salamanders.
• Dissertation: Investigating the Performance of Survival Regression Models Under Multiple, Simultaneous Assumption Violations.
• Sugar-Sweetened Beverage and Sugar Consumption and Colorectal Cancer Incidence and Mortality According to Anatomic Subsite.
• Is the Future of Peer Review Automated?

Announcements

• WORKSHOP SERIES: The Role of Plant Agricultural Practices on Development of Antimicrobial Resistant Fungi Affecting Human Health.
• 8th Annual Diabetes Symposium - August 5, 2022.
• Applications Open: Strengthening Causal Inference in Behavioral Obesity Research Short Course 2022.

Featured

• Dietary Restriction and the Transcription Factor Clock Delay Eye Aging to Extend Lifespan in Drosophila melanogaster.
• The Effects of Graded Levels of Calorie Restriction XVIII: Tissue Specific Changes in Cell Size and Number in Response to Calorie Restriction.
• Does Maternal Nutrition Have Any Impact on Sex Ratio at Birth in Animal and Human Studies?
• A Fat-Promoting Botanical Extract from Artemisia scoparia Exerts Geroprotective Effects on Caenorhabditis elegans Life Span and Stress Resistance.

Headline vs Study

• Headline: Brain’s Wiring, Not Lack of Willpower, May Drive Obesity: Study.
• Study: Grant Award. No Study (yet).

Contrary or Null Findings

• RCT: Null Effects in Full Sample in Low vs Moderate Dose of Recreational Football on Cardiovascular Risk Factors.
• RCT: "There were no differences in excessive gestational weight gain observed between groups when analyzing participants in aggregate."
• RCT: The Role of Physical Activity in Long-Term Weight Loss: Null 36-Month Results.
• RCT: Limited to No Effects of Response Inhibition Training Following Binge Memory Retrieval in Young Adults Binge Eaters.
• RCT: "Pasture versus Grain origins of the beef had little influence on participants' responses."
• RCT: "Among Latino men with overweight and obesity, HOMBRE was not more effective for clinically significant weight loss than a minimal-intensity intervention at 18 months."
• Low-Dose Gallic Acid Administration Does Not Improve Diet-Induced Metabolic Disorders and Atherosclerosis in ApoE Knockout Mice.
• New Measures, Old Conclusions: Obesity Does Not Worsen Outcomes After Elective Abdominal Aortic Aneurysm Repair.

Basic

• Severe Muscle Deconditioning Triggers Early Extracellular Matrix Remodeling and Resident Stem Cell Differentiation Into Adipocytes in Healthy Me.
• Exercise Protects Intestinal Epithelial Barrier from High Fat Diet-Induced Permeabilization Through SESN2/AMPKα1/HIF-1α Signaling.
• Downregulation of Peripheral Lipopolysaccharide Binding Protein Impacts on Perigonadal Adipose Tissue Only in Female Mice.
• β-Elemene Regulates M1-M2 Macrophage Balance Through the ERK/JNK/P38 MAPK Signaling Pathway.
• The Effects of Brewers’ Spent Grain on High-Fat Diet-Induced Fatty Liver.
• The Impact of High Fat Consumption on Neurological Functions Following a Traumatic Brain Injury in Rats.
• IDF21-0176 Spatial Memory Impairment in Type 2 Diabetic Rats Is Associated with Adiposity and Altered Glucose Metabolism.

Scientific Rigor & Scholarly Dialogue

• "Clarification on our critique of the Energy Balance Hypothesis of Obesity”.
• Controversial Supplements Researcher Not Guilty of Misconduct, Canadian University Concludes.
• Retraction: Caloric Restriction Reverses Obesity-Induced Mammary Gland Inflammation in Mice.
• Preprint: Replication Concerns in Sports Science: A Narrative Review of Selected Methodological Issues in the Field.

Clinical

• Changes in Adiponectin:Leptin Ratio Among Older Adults with Obesity Following a 12-Month Exercise and Diet Intervention.
• Obesity Subtyping: The Etiology, Prevention, and Management of Acquired Versus Inherited Obese Phenotypes.
• Meta-Analysis of RCTs: Effects of Self-Care Programs on the Incidence of Diabetes Among Adults with Prediabetes.

Children and Adolescents

• Childhood Obesity: A Review of Current and Future Management Options.
• Effect of an Interactive Mobile Health Support System and Daily Weight Measurements for Pediatric Obesity Treatment.
• Measuring Change in Adolescent Physical Activity: Responsiveness of a Single Item.
• What Do Health Professionals and Parents Want as Part of an Online Childhood Obesity Prevention Program?
• The Genetics of Type 2 Diabetes in Youth: Where We are and the Road Ahead.
• Review: Avoidant/Restrictive Food Intake Disorder —Strategies for Dietary Management in Children.
• Meta-Analysis of RCTs: Effects of Physical Exercise on Cardiometabolic Biomarkers and Inflammatory Markers in Children.
• Review: The Effects of Nutrition on Linear Growth.

Surgery

• Comparison of Weight Loss Outcomes between Roux-En-Y Gastric Bypass and Sleeve Gastrectomy in a Racially Mixed Urban Patient Population.
• The Cost-Effectiveness of Surgical Weight Loss Interventions for Patients with Knee Osteoarthritis and Class III Obesity.
• Changes of Short-Chain Fatty Acids and Their Receptors in an Obese Rat Model After Sleeve Gastrectomy.
• Body Composition, Mitochondrial Oxygen Metabolism and Metabolome of Patients with Obesity Before and After Bariatric Surgery.
• Review: Regulation of Body Weight: Lessons Learned from Bariatric Surgery.
• Meta-Analysis: Sex Difference in the Safety and Efficacy of Bariatric Procedures.

Drugs

• Long-Term Impact of Laparoscopic Sleeve Gastrectomy on Drug Costs of Japanese Patients with Obesity and Type 2 Diabetes Mellitus.
• A National Survey on Current Clinical Practice Pattern of Korean Medicine Doctors for Treating Obesity.
• Tirzepatide Once Weekly for the Treatment of Obesity.
• Once-Weekly Dulaglutide for the Treatment of Youths with Type 2 Diabetes.
• Evaluating Anti-Obesity Potential, Active Components, and Antioxidant Mechanisms of Moringa peregrina Seeds Extract on High-Fat Diet-Induced Obesity.

Food & Diet

• Women with Obesity Have a High Carbohydrate Intake Without Changes in the Resting Metabolic Rate in the Luteal Phase.
• Multiple Metrics of Carbohydrate Quality Place Starchy Vegetables Alongside Non-Starchy Vegetables, Legumes, and Whole Fruit.
• Secondary Analysis of RCT: The Effect of Nigella sativa on Total Antioxidant Capacity and Malondialdehyde in Women with Overweight and Obesity.
• Perspective: Vegan Diets for Older Adults? Potential Impact on Muscle Mass and Strength.

Caloric and Dietary Restriction

• Modulation of Nigral Dopamine Signaling Mitigates Parkinsonian Signs of Aging: Evidence from Intervention with Calorie Restriction or Inhibition of Dopamine Uptake.
• Perspective: Time-Restricted Eating—Integrating the What with the When.

Exercise & Physical Activity

• Concurrent Training Promotes Greater Gains on Body Composition and Components of Physical Fitness Than Single-Mode Training (Endurance or Resistance) in Youth with Obesity.
• Determinants of Dropout from and Variation in Adherence to an Exercise Intervention.
• Meta-Analysis of RCTs: Effects of Exercise Training on Glycaemic Control in Youths with Type 1 Diabetes.
• Review: Influence of Nutritional Status and Physical Exercise on Immune Response in Metabolic Syndrome.

Economics & Sociology

• Comorbid Depression and Obesity Among Adults in Germany: Effects of Age, Sex, and Socioeconomic Status.
• How Socioeconomic Status and Acculturation Relate to Dietary Behaviors Within Latino Populations.

Epidemiology

• Changes in Obesity Prevalence Attributable to Ultra-Processed Food Consumption in Brazil between 2002 and 2009.
• Genetic Determinants of BMI and Fasting Glucose are Mediators of Grade 1 Diastolic Dysfunction.
• Lifetime BMI and Grip Strength at Age 46 Years.

Psychology & Neuroscience

• Supplementing a Widely Available Weight Loss Program with Gamified Inhibitory Control Training.
• Circulating FGF21 Vs. Stress Markers in Girls During Childhood and Adolescence, and in Their Caregivers: Intriguing Inter-Relations between Overweight/Obesity, Emotions, Behavior, and the Cared-Caregiver Relationship.
• Altered Intrinsic Regional Spontaneous Brain Activity in Patients with Severe Obesity and Meibomian Gland Dysfunction.
• Early Childhood Dietary Intake and Subsequent Socioemotional and Cognitive School Readiness Among Australian Children.
• Review: A Neuroeconomics Approach to Obesity.

Equity and Disparities

• "Future work should evaluate African Americans' experience with nutrition-focused policy, systems, and environmental changes...which may be better able to address racial disparities in obesity and food insecurity."
• Determinants and Consequences of Food and Nutrition Insecurity in Justice-Impacted Populations.
• Impact of Trends and Gender Disparity in Obesity on Future Type 2 Diabetes in Turkey.

Stigma

• Weight Stigma and Posttraumatic Stress Disorder Symptoms in Individuals Seeking Bariatric Surgery.
• Development and Validation of the Fat Attitudes Assessment Toolkit (FAAT): A Multidimensional Nonstigmatizing Measure of Contemporary Attitudes Toward Fatness and Fat People.
• Describing the Views of Canadian Post-Secondary Students in Health-Related Disciplines on the Recognition of Obesity as a Chronic Disease.

Policy Related

• Identifying Strategies for Facilitating Physical Activity Among Older Adults.
• Are Front-Of-Pack Labels a Health Policy Tool?
• Comment on Muzzioli et al. Are Front-Of-Pack Labels a Health Policy Tool? Nutrients 2022, 14, 771.
• Review: Front-Of-Pack Labelling Systems to Improve the Quality of Nutrition Information to Prevent Obesity.

Intergenerational Effects

• The Prenatal Neighborhood Environment and Geographic Hotspots of Infants with At-Risk Birthweights in New York City.
• Underreporting of Energy Intake Increases over Pregnancy.
• Pregnancy Homocysteine and Cobalamin Status Predict Childhood Metabolic Health in the Offspring.
• Influence of Parental Weight Change on the Incidence of Overweight and Obesity in Offspring.
• Parenting Styles in Relation to Childhood Obesity, Smoking and Drinking.
• Maternal Glycemic Spectrum and Adverse Pregnancy and Perinatal Outcomes in a Multiracial US Cohort.
• Meta-Analysis: The Effect of Dietary Patterns on Clinical Pregnancy and Live Birth Outcomes in Men and Women Receiving Assisted Reproductive Technologies.

Ecology, Evolution, & Energetics

• Let’s Play at Digging. How Vigorous Is This Energetic Task for a Young Forager?
• Racing Time: Physiological Rates and Metabolic Scaling in Marine Mammals.

Methods

• Characteristics of Body Composition Estimated by Air-Displacement Plethysmography in Chinese Preschool Children.
• Learning from Missing Data: Examining Nonreporting Patterns of Height, Weight, and BMI Among Canadian Youth.
• Update on Analytical Methods and Research Gaps in the Use of Household Consumption and Expenditure Survey Data to Inform the Design of Food-Fortification Programs.
• Implementation of Physical Activity on Prescription for Children with Obesity in Paediatric Health Care: Protocol for a Feasibility and Evaluation Study Using Quantitative and Qualitative Methods.
• Assessment of Inequity in Bicyclist Crashes Using Bivariate Bayesian Copulas.

Commentary

• The Avocado-Cancer Link: Is This Fruit Cancer-Protective?
• The Effects of Phosphorus in Cardiovascular and Renal Health.
• The Immune Response in Adipocytes and Their Susceptibility to Infection: A Possible Relationship with Infectobesity.
• Evaluating the Evidence on Beverage Taxes: Implications for Public Health and Health Equity.
• Climate Change Is Coming for Your Pizza Sauce.
• Fatty Acids Activate All but One Member of the KV7 Family of Ion Channels.
• Salmonella Vaccine for Poultry Contributed to Rise of Antibiotic-Resistant Bacteria, Researchers Report.
• Bias of Obesity Professionals: A Fork in the Road?

General

• The Organizational Evolution of Small Food Buying Clubs.
• Fetal-Placental Antigens and the Maternal Immune System: Reproductive Immunology Comes of Age.
• A Meiotic Driver Alters Sperm Form and Function in House Mice: A Possible Example of Spite.
• Food: Nourishment, Poverty, Love, and Hope in Gods of Green County.
• Short-Necked Giraffe Relative Discovered in China. It Used Its Helmet Head to Bash Rivals.
• Focus on the ‘Why’ and You Will Work with Great Passion and Focus.
• How Science Fuels a Culture of Misinformation.
• The Good Science Project Interview with David Allison.

Announcements

• Nutrition 2022 Live Online Program [June 14-16].
• IU Bloomington School of Public Health Recruiting for Many Staff Opportunities - COME JOIN US!
• Applications Open: Strengthening Causal Inference in Behavioral Obesity Research Short Course 2022.

Featured

• Anthropometric Evaluation of a 3D Scanning Mobile Application.
• Fragmented Day-Night Cycle Induces Reduced Light Avoidance, Excessive Weight Gain During Early Development, and Binge-Like Eating During Adulthood in Mice.
• Diet Quality of NCAA Division I Athletes Assessed by the Healthy Eating Index.

Headline vs Study

• Headline: Junk Food in Reality TV Could Be Fueling Obesity.
• Study: Assessment of Alcohol, Tobacco and Foods High in Fat, Sugar or Salt in 20 Reality TV Programs from 2019-2020. Obesity Not Assessed.

Contrary or Null Findings

• RCT: "The worksite intervention, implemented during meal breaks, did not reduce BMI or other clinical indicators."
• RCT: Vitamin D Does Not Prevent Type 2 Diabetes in High-Risk Adults, Trial Finds.
• Lifestyle Changes, Meds Effective to Prevent or Delay Type 2 Diabetes; No Change in CVD.
• Exercise Training Worsens Cardiac Performance in Males but Does Not Change Ejection Fraction and Improves Hypertrophy in Females in a Mouse Model of Metabolic Syndrome.
• Lowering Blood Cholesterol Does Not Affect Neuroinflammation in Experimental Autoimmune Encephalomyelitis.
• Mpagliflozin Does Not Reverse Lipotoxicity-Induced Impairment in Human Myeloid Angiogenic Cell Bioenergetics.
• "Contrary to previous studies, we did not find significant cicada effects on tree performance despite observing higher plant available nutrient levels on cicada addition plots."
• "Contrary to predictions, pike grew faster at high food levels when they had previously experienced low food levels and downregulated their RMR."

Basic

• Multiomics Reveals Persistence of Obesity-Associated Immune Cell Phenotypes in Adipose Tissue During Weight Loss and Weight Regain in Mice.
• Sleeve Gastrectomy Improves High-Fat Diet–Associated Hepatic Steatosis Independent of the Glucagon-Like-Petpide-1 Receptor in Rats.
• MPST Sulfurtransferase Maintains Mitochondrial Protein Import and Cellular Bioenergetics to Attenuate Obesity.
• Modeling Human Heterogeneity of Obesity with Diversity Outbred Mice Reveals a Fat Mass-Dependent Therapeutic Window for Resolvin E1.

Scientific Rigor & Scholarly Dialogue

• Correction: The Best Drug Supplement for Obesity Treatment: A Systematic Review and Network Meta-Analysis.
• Letter: Let's Be Clear About Expected Cardiovascular Risk: A Commentary on the Massive Rise in LDL Cholesterol Induced by Carbohydrate Restriction in the Proposed “Lean Mass Hyper-Responder” Phenotype.
• Letter: Evidence for a Lean Mass Hyperresponder Phenotype Is Lacking with Increases in LDL Cholesterol of Clinical Significance in All Categories of Response to a Carbohydrate-Restricted Diet.
• Response: Reply to M Mindrum and J Moore et al.
• Perspective: The Glycemic Index Falls Short as a Carbohydrate Food Quality Indicator to Improve Diet Quality.

Clinical

• Age- and Sex-Specific Effects of a Long-Term Lifestyle Intervention on Body Weight and Cardiometabolic Health Markers in Adults with Prediabetes.
• RCT: Effect of a Ketogenic Diet Versus Mediterranean Diet on HbA1c in Individuals with Prediabetes and Type 2 Diabetes Mellitus.

Children and Adolescents

• Association between Hyperglycaemia in Pregnancy and Growth of Offspring in Early Childhood.
• Association of Smartphone Use with Body Image Distortion and Weight Loss Behaviors in Korean Adolescents.

Surgery

• Current Applications of Artificial Intelligence in Bariatric Surgery.
• Influence of NAFLD and Bariatric Surgery on Hepatic and Adipose Tissue Mitochondrial Biogenesis and Respiration.
• A Long-Term Prospective Study to Understand the Psychosocial, Environmental, Health and Behavioural Predictors of Weight Loss and Regain in Patients Who Have Bariatric Surgery.
• Roux-En-Y Gastric Bypass as a Treatment for Hepatic Iron Overload.

Drugs

• Guanabenz—an Old Drug with a Potential to Decrease Obesity.
• Utility of an Experimental Medicine Model to Evaluate Efficacy, Side-Effects and Mechanism of Action of Novel Treatments for Obesity and Binge-Eating Disorder.
• Medicines for Long-Term Obesity Management.

Food & Diet

• Flavonoid–Amyloid Fibril Hybrid Hydrogels for Obesity Control Via the Construction of Gut Microbiota.
• Effect of Carbohydrate-Restricted Diets and Intermittent Fasting on Obesity, Type 2 Diabetes Mellitus, and Hypertension Management: Consensus Statement of the Korean Society for the Study of Obesity, Korean Diabetes Association, and Korean Society of Hypertension.
• Functional Yogurt Fermented by Two-Probiotics Regulates Blood Lipid and Weight in a High-Fat Diet Mouse Model.
• Effect of Different Food Groups on Energy Intake Within and Between Individuals.
• Sour Grapes: Addressing the Challenges in Utilising Vinegar and Short-Chain Fatty Acids to Treat Dysregulated Glycaemic Responses.

Caloric and Dietary Restriction

• Intermittent Methionine Restriction Reduces IGF-1 Levels and Produces Similar Healthspan Benefits to Continuous Methionine Restriction.
• Calorie Restriction Changes the Anxiety-Like Behaviour of Ageing Male Wistar Rats in an Onset- and Duration-Dependent Manner.

Exercise & Physical Activity

• Racial and Ethnic Differences in the Relationship between Neighborhood Environment and Physical Activity Among Middle-Aged and Older Adults.
• Longitudinal Associations of Childhood Fitness and Obesity Profiles with Midlife Cognitive Function.
• RCT: The Role of Physical Activity in Long-Term Weight Loss.

Economics & Sociology

• The Likely Fiscal and Public Health Effects of an Excise Tax on Sugar-Sweetened Beverages in Kenya.
• The Potential Epidemiologic, Clinical, and Economic Impact of Requiring Schools to Offer Physical Education (PE) Classes in Mexico City.
• Cross-National Variation in the Association between Family Structure and Overweight and Obesity.

Epidemiology

• Long-Term Metabolic Fate and Mortality in Obesity Without Metabolic Syndrome.
• Meta-Analysis: Association of BMI with Clinical Outcomes in Patients with Cystic Fibrosis.

Psychology & Neuroscience

• Review: Utility of ‘Substance Use Disorder’ as a Heuristic for Understanding Overeating and Obesity.
• Healthy Habits Associated with Successful Weight Loss Maintenance on a Commercial Program.
• Economic and Social Deprivation Predicts Impulsive Choice in Children.
• Downregulation of Fat Mass and Obesity-Related Protein in the Anterior Cingulate Cortex Participates in Anxiety- and Depression-Like Behaviors Induced by Neuropathic Pain.

Equity and Disparities

• Review: Equity in Agriculture-Nutrition-Health Research.
• Review: Advancing Equity in Blood Pressure Control.
• Obesity and Eligibility for Obesity Treatments Among Adults with Disabilities in the U.S.

Stigma

• RCT: Internalized Weight Stigma in Women with Class III Obesity: A Virtual Lifestyle Modification Intervention Followed by a Mindful Self-Compassion Intervention.
• Obesity Management: At the Forefront Against Disease Stigma and Therapeutic Inertia.
• Weight Stigma in Children and Adolescents Recommendations for Practice and Policy.

Policy Related

• Policy, Systems, and Environmental Change Strategies in the Supplemental Nutrition Assistance Program-Education (SNAP-Ed).
• The Evolution of Food Security: Where are We Now, Where Should We Go Next?

Intergenerational Effects

• Maternal Secretin Ameliorates Obesity by Promoting White Adipose Tissue Browning in Offspring.
• Association of Prepregnancy Obesity and Remodeled Maternal-Fetal Plasma Fatty Acid Profiles.
• Infant Mesenchymal Stem Cell Insulin Action Is Associated with Maternal Plasma Free Fatty Acids, Independent of Obesity Status.

Ecology, Evolution, & Energetics

• Ecology, Protein Leverage, and Public Health.
• The Active Mouse Rests Within: Energy Management Among and Within Individuals.

Methods

• Meta-Analysis: Twenty-Four-Hour Urinary Sodium and Potassium Excretion in Children and Young People.
• Feasibility of the Automatic Ingestion Monitor (AIM-2) for Infant Feeding Assessment: A Pilot Study Among Breastfeeding Mothers from Ghana.

Mathematical and Quantitative

• Dynamical Analysis of Tumor Model with Obesity and Immunosuppression.
• Using Agent-Based Modeling to Extrapolate Community-Wide Impact from a Stakeholder-Driven Childhood Obesity Prevention Intervention.
• Use of Physiologically-Based Pharmacokinetic Modeling to Inform Dosing of the Opioid Analgesics Fentanyl and Methadone in Children with Obesity.

Commentary

• Take Herbal Supplements with a Dose of Caution.
• For Triglycerides, “Normal” May Not Be “Optimal”.
• Does Metformin Have Any Role in Alzheimer's Disease?
• Modern Perspectives on Adiponectin: Targeting Obesity, Diabetes, and Cancer Together Using Herbal Products.
• Mammalian Tumor-Like Organs. 2. Mammalian Adipose Has Many Tumor Features and Obesity Is a Tumor-Like Process.
• Obesity and Male Infertility: Multifaceted Reproductive Disruption.
• A Boom in Fitness Trackers, a Bust in Fitness.
• Diabetes Drug Improves Antibacterial Treatment Speed and Effectiveness, Researchers Report.
• Providing Free School Meals to Wealthy Students Does Not Help Children in Need.

General

• Vertebral Body Adherent Allogeneic Mesenchymal Stromal Cells Increase in Vivo Perfusion and Improve Muscle Function in Diabetic Mouse Models of Critical Limb-Threatening Ischemia.
• IU Study Explored How People's Beliefs Impact Overdose Education and Naloxone Distribution Programs.
• Dolphins Can Identify Their Friends by Taste, Study Shows for the First Time.
• Cool Science: Paper Airplanes, Insect Wings and the Future of Tiny Drones.
• Pursuing an Evidence-Informed Approach to the Prevention of Gun Violence.
• Wild Animals are Evolving Faster Than Anybody Thought.
• "The second law of thermodynamics is among the most sacred in all of science, but it has always rested on 19th century arguments about probability."
• A Rethink of Cause and Effect Could Help When Things Get Complicated.

Aging

• Systematic Review: Contribution of Biological Age-Predictive Biomarkers to Nutrition Research: Current Evidence and Implications for Future Research and Clinical Practice.
• Preprint: The damage-independent evolution of ageing by selective destruction.

Announcements

• New Book: To Err Is Human, To Admit It Is Not and Other Essays: Thoughts on Criminal Justice, Health, Holidays, Nature, and the Universe Paperback – by Steven N. Austad.

Featured

• The Simplistic View of Obesity Management: A Curse in Disguise.
• The Overlooked Variable in Animal Studies: Why Diet Makes a Difference.
• Accelerating Animal Energetics: High Dive Costs in a Small Seabird Disrupt the Dynamic Body Acceleration - Energy Expenditure Relationship.(pdf)
• RCT: Sperm Count Is Increased by Diet-Induced Weight Loss and Maintained by Exercise or GLP-1 Analogue Treatment.
• Evaluating the Process to Develop the Dietary Guidelines for Americans, 2020–2025.

Headline vs Study

• Headline: Everyone Eats Three Extra Cheeseburgers a Day Than They Admit, Study Shows.
• Study: Estimates of Underreporting When Accounting for Allometric Scaling. Daily Cheeseburger Underreporting Not Described.

Contrary or Null Findings

• An Isoproteic Cocoa Butter-Based Ketogenic Diet Fails to Improve Glucose Homeostasis and Promote Weight Loss in Obese Mice.
• Meta-Analysis: No Major Differential Effects of Intermittent Fasting in Humans Compared to Caloric Restriction.
• Heat Acclimation in Females Does Not Limit Aerobic Exercise Training Outcomes.
• "...increased BMI is not positively associated with a greater odds of developing sarcoidosis." (pdf)
• BMI Is Not an Independent Factor Associated with Recovery Room Length of Stay for Patients Undergoing Outpatient Surgery.
• "The findings suggest that in diabetes patients increase in BMI alone does not lead to any alterations in their lipid profile."
• RCT: Resistance Training with or Without Nutritional Supplementation Showed No Influence on Muscle Thickness in Old Institutionalized Adults. A Secondary Analysis of the Vienna Active Ageing Study.
• "Highest quartile of percentage of energy intake from UPF [ultra-processed food] (PEI-UPF) was not significantly correlated with maternal GWG (p=0.215), infant QMR fat (p=0.816) and lean mass (p=0.423) or ADP fat (p=0.482) or fat-free mass (p=0.835)."

Basic

• Monochromatic Blue Light Not Green Light Exposure Is Associated with Continuous Light-Induced Hepatic Steatosis in High Fat Diet Fed-Mice Via Oxidative Stress.
• Deletion of GPR30 Drives the Activation of Mitochondrial Uncoupling Respiration to Induce Adipose Thermogenesis in Female Mice.
• IL-1R-IRAKM-Slc25a1 Signaling Axis Reprograms Lipogenesis in Adipocytes to Promote Diet-Induced Obesity in Mice.
• Calorie Restriction and Calorie Dilution Have Different Impacts on Body Fat, Metabolism, Behavior, and Hypothalamic Gene Expression.
• Differential Effects of Acute Versus Chronic Dietary Fructose Consumption on Metabolic Responses in FVB/N Mice.
• Adolescent Obesity Incurs Adult Skeletal Deficits in Murine Induced Obesity Model.

Scientific Rigor & Scholarly Dialogue

• Overview of Objective Measurement Technologies for Nutrition Research, Food-Related Consumer and Marketing Research.
• Adjusting for Collider Bias in Genetic Association Studies Using Instrumental Variable Methods.
• Letter: Common Errors and Pitfalls in Observational Studies Examining the Association of Medical Nutrition Therapy with Outcomes in Critically Ill Patients.
• Response: Reply to W. H. Hartl.
• Fixing Food Deserts: Promising or Trivial Effects?

Clinical

• RCT: Intervention Targeting Appetitive Traits on BMI Among Adults with Overweight or Obesity.
• Systematic Review: The Effectiveness of Weight Loss Programs for Low Back Pain.

Children and Adolescents

• Meta-Analysis: The Effectiveness of E-health Interventions for the Treatment of Overweight or Obesity in Children and Adolescents.
• Distinct Causal Effects of Body Fat Distribution on Cardiometabolic Traits Among Children.
• Systematic Review: Methods for the Economic Evaluation of Obesity Prevention Dietary Interventions in Children.
• Degree of Food Processing and Association with Overweight and Abdominal Obesity in Adolescents.

Surgery

• Development and Validation of an Artificial Intelligence-Based Model to Predict Gastroesophageal Reflux Disease After Sleeve Gastrectomy.
• Vertical Sleeve Gastrectomy Lowers SGLT2/Slc5a2 Expression in the Mouse Kidney.
• Effect of Meal Texture on Postprandial Glucose Excursions and Gut Hormones After Roux-En-Y Gastric Bypass and Sleeve Gastrectomy.
• Meta-Analysis: Bariatric Surgery and Cardiovascular Disease.

Drugs

• Impact of Antiseizure Medications on Appetite and Weight in Children.
• Cardiovascular Outcomes in Patients Initiating First-Line Treatment of Type 2 Diabetes with Sodium–Glucose Cotransporter-2 Inhibitors Versus Metformin: A Cohort Study.

Food & Diet

• Audio: When Climate Change Reaches Your Plate.
• Diverse Impact of N-Acetylcysteine or Alpha-Lipoic Acid Supplementation During High-Fat Diet Regime on Fatty Acid Transporters in Visceral and Subcutaneous Adipose Tissue.
• Antiobesity, Antihyperglycemic, and Antidepressive Potentiality of Rice Fermented Food Through Modulation of Intestinal Microbiota.
• Nicotinamide Reprograms Adipose Cellular Metabolism and Increases Mitochondrial Biogenesis to Ameliorate Obesity (in Mice).
• Association between Vitamin D and Adiponectin and Its Relationship with BMI.
• Meta-Analysis: Low Glycemic Index and Glycemic Load Diets in Adults with Excess Weight.

Caloric and Dietary Restriction

• Short-Term Moderate Caloric Restriction in a High-Fat Diet Alleviates Obesity Via AMPK/SIRT1 Signaling in White Adipocytes and Liver.
• Calorie Restriction and Calorie Dilution Have Different Impacts on Body Fat, Metabolism, Behavior, and Hypothalamic Gene Expression.
• RCT: Cardiometabolic Effects of Early Vs. Delayed Time-Restricted Eating Plus Caloric Restriction in Adults with Overweight and Obesity.

Exercise & Physical Activity

• Weights Can Be Weapons in Battle Against Obesity.
• Meta-Analysis: Factors That Moderate the Effect of Nitrate Ingestion on Exercise Performance in Adults.
• RCT: Influence of Diet on Acute Endocannabinoidome Mediator Levels Post Exercise in Active Women.
• RCT: Effects of Pre-Surgical Aerobic Dance-based Exercise on Lower Extremity in People with Morbid Obesity Awaiting Bariatric Surgery.
• Duration of an Acute Moderate-Intensity Exercise Session Affects Approach Bias Toward High-Calorie Food Among Individuals with Obesity.

Economics & Sociology

• Socioeconomic Status and Eating Disorder Prevalence: At the Intersections of Gender Identity, Sexual Orientation, and Race/ethnicity.
• Systematic Review: Cultural Factors Related to Childhood and Adolescent Obesity in Mexico.
• Socioeconomic Differences in the Association between Maternal Age and Maternal Obesity: A Register-Based Study of 707,728 Women in Finland.
• Scoping Review: Family Socioeconomic Status and Childhood Adiposity in Europe.

Epidemiology

• Hypertension Modifies the Associations of BMI and Waist Circumference with All-Cause Mortality Among Older Chinese: A Retrospective Cohort Study.
• Obesity and Accelerated Epigenetic Aging in a High-Risk Cohort of Children.
• Temporal Relationship Among Adiposity, Gut Microbiota, and Insulin Resistance in a Longitudinal Human Cohort.

Psychology & Neuroscience

• Association of Food Insecurity and Food Addiction Symptoms: A Secondary Analysis of Two Samples of Low-Income Female Adults.
• RCT: Physical and Mental Health Outcomes of an Integrated Cognitive Behavioural and Weight Management Therapy for People with an Eating Disorder Characterized by Binge Eating and a High BMI.
• Long-Term Priming of Hypothalamic Microglia Is Associated with Energy Balance Disturbances Under Diet-Induced Obesity.

Equity and Disparities

• Neighborhood Deprivation and Obesity: Sex-Specific Effects of Cross-Sectional, Cumulative and Residential Trajectory Indicators.
• Anti-Obesity Medication Prescriptions by Race/ethnicity and Use of an Interpreter in a Pediatric Weight Management Clinic.

Stigma

• Book Chapter: Bias, Stigma, and Social Consequences of Obesity.
• Weight Stigma in Children and Adolescents: Recommendations for Practice and Policy.

Policy Related

• Use of Food and Nutrition Labels Among Urban Mongolian Supermarket Shoppers: Implications for Food Labeling Policy and Practice.
• Perspective: Overcoming Congressional Inertia on Obesity Requires Better Literacy in Obesity Science.

Intergenerational Effects

• The Influence of Parental Body Composition and Lifestyle on Offspring Growth Trajectories.
• Nutrition During Pregnancy and Lactation: New Evidence for the Vertical Transmission of Extra Virgin Olive Oil Phenolic Compounds in Rats.
• The Mediating Effect of DNA Methylation in the Association between Maternal Sleep During Pregnancy and Offspring Adiposity Status: A Prospective Cohort Study.

Ecology, Evolution, & Energetics

• Complications with Body-Size Correction in Comparative Biology: Possible Solutions and an Appeal for New Approaches.
• Physiological Effects of Food Availability Times in Higher Vertebrates.

Methods

• Systematic Review: Methods Used to Assess and Report Dietary Patterns.
• Validating Dietary Assessment Tools with Energy Expenditure Measurement Methods: Is This Accurate?

Mathematical and Quantitative

• Leptin Effect’s on Glucose and Insulin Kinetics: A Mathematical Model.
• The Impact of Media Coverage on Obesity.

Commentary

• Intro to Lipids & Lipoproteins: Why There Is No ‘Bad’ or ‘Good’ Cholesterol.
• Audio: How Restaurant Menus Mirror Our Warming Ocean.
• Do You Love or Loathe Coffee? Your Genes May Be to Blame.
• Food Cues in the Eat-More Food Environment.
• Infant and Child Formula Shortages: Now Is the Time to Prevent Recurrences.
• Tirzepatide Pricing Comes in Similar to Semaglutide.
• Podcast: "Anti-Aging" Drugs — NAD+, Metformin, & Rapamycin.
• Alzheimer's Disease: The Inevitable Presence of Absence (Does Metformin Have a Role in Alzheimer's Disease?).(pdf)

General

• Dissertation: A Toxicogenomic Analysis of the Hepatic Response to Triclosan.
• Insights from a High-Fat Diet Fed Mouse Model with a Humanized Liver.
• Musings on Mentoring: Teach Your “Children” Well.
• Fluid Balance Is Unlikely Modified by the Menstrual Cycle When Ad Libitum Drinking Is Permitted During Physical Work in the Heat.
• Urban-Adapted Mammal Species Have More Known Pathogens.
• Your Brain Operates at the Edge of Chaos, but That's Not a Bad Thing.
• Effects of Prior Exposure to Conflicting Health Information on Responses to Subsequent Unrelated Health Messages: Results from a Population-Based Longitudinal Experiment.
• Rising Temperatures Erode Human Sleep Globally.

Announcements

• Regenstrief and Indiana University Study Explores Eating, Drinking, and Physical Activity Among Middle Aged Women Living with Obesity and Urban Poverty.
• Applications Open: 2022 Mathematical Sciences in Obesity Research Short Course.
• Applications Open: Strengthening Causal Inference in Behavioral Obesity Research Short Course 2022.